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Beyond sleep problems, melatonin supplements have been tried in various clinical situations in patients with schizophrenia such as alleviation of antipsychotic-induced metabolic adverse effects, alleviation of tardive dyskinesia, amelioration of cognitive dysfunction, and discontinuation or reduction of benzodiazepines

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RNA was quantified with Nanodrop 1,000 (Thermo Fisher Scientific) and only the samples meeting the criteria of OD 260/280 ratios between 1.8 and 2.0 were used for cDNA synthesis

So the evidence is there